Here is a list of games I consider to be system sellers and are therefore among my favorites. I will begin with last generation systems and continue on to systems for which games are still being actively developed. All of these systems include many other games worthy of attention but I would not exactly consider to be system sellers. I am only including games exclusive to each system:
Nintendo Game Cube:
-The Legend of Zelda: The Wind Waker
-The Legend of Zelda: Twilight Princess
-Resident Evil 4 (this is an exception to the system specific rule as it was released on GC so long before PS2 and is the superior version.)
Playstation 2:
-ICO
-Shadow of the Colossus
-Okami (another soon to be exception to the exclusivity rule but I don't consider the Wii to be a proper gaming system for games that were not specifically designed for it's "unique" controls. If you can't tell, I'm still bitter over the GC Twilight Princess delay because of the friggin Wii version.)
-Odin Sphere (this game proves that sprites aren't dead and just how beautiful a 2D game can be on current systems. We need a revival of sprite-based 2D games like this.)
-Devil may cry 1, 2, 3 Special Edition
-MGS3: Subsistance
-Ace Combat 4, 5
-Final Fantasy X, XII (For FF fans only, though this goes without saying. I felt I had to at least include FFX as it was the first PS2 game I ever owned.)
XBOX:
-Crimson Skies: High Road to Revenge
-Psychonauts
-Thief: Deadly Shadows
-Otogi 1, 2
-Halo 1, 2
-Ninja Gaiden (Black)
Game Boy Advance:
-Advance Wars 1, 2
-Fire Emblem (Both games)
-Super Robot Taisen: Original Generation 1, 2
-The Legend of Zelda: The minish cap
-Boktai 1, 2
Nintendo DS:
-Advance Wars: Dual Strike
-Advance Wars: Days of Ruin
-Castlevania: Dawn of Sorrow
-Castlevania: Portrait of Ruin
-Lunar Knights
-The Legend of Zelda: Phantom Hourglass
PSP:
-Loco Roco
-Patapon
-flOw (available by download only for those interested)
X360:
-Gears of War 1&2
-Halo 3
PS3:
-MGS4
-Uncharted 2: Among Thieves
-Resistance 1&2
-The Last Guardian
DarCowAlways