- Mike is the writer for the first episode of his show, The Mike O'Malley Show. Mike was also the Executive Producer for the show.
- Mike directed the series finale of Yes, Dear, entitled "Should I Bring a Jacket?".
- Mike had his own television show called The Mike O'Malley Show, but it ended up getting cancelled after only two episodes.
- Mike is 5'10" feet tall.
- Mike is a member of the Kappa Sigma Fraternity.
- Mike has been in the acting business since the year of 1991.
- Mike is a Boston Red Sox fan. He is actually a member of the Red Sox Nation and has even thrown out the first pitch at a game in May of 2006.
- Mike O'Malley has been featured in the films: The Perfect Man, 28 Days, Pushing Tin, Deep Impact and Above Freezing.
- Mike O'Malley has written three off-Broadway plays, "Three Years From Thirty", "Diverting Devotion", & "Searching for Certainty".
- The Simpsons have made frequent remarks on their show poking fun at Mike O'Malley.
- Mike is also a spokesman for ESPN.
- Mike appears in the commericals on ESPN promoting the ESPY Awards.
- Mike is known as "The Rick," the all around Boston sports Fanatic in some "ESPN" commercials.
- Appears in the Alan Jackson music video as the car repairman for the song "The Talkin' Song Repair Blues".
- Mike also played a part in a movie with Sandra Bullock called 28 Days.
- Mike's wife, Lisa gave birth to their second child, a boy, Seamus back in December of 2004.
- His father, Tony, is a retired defense-industry executive.
His mother, Marianne, is a career counselor.
- Studied theater at the University of New Hampshire.
- When Mike appeared as a guest on "The Late Late Show" with Craig Kilburn and said he was just married. [17 May 2001]
- Mike was raised in New Hampshire.
- Mike attended the University of New Hampshire in 1984.
- Mike's Trade mark is he always wears a baseball cap because he is bald.
- Mike's nickname is "The Rick".