Actor
| 1. | Gamer (2009) | |
| 2. | The Game Plan (2007) as Stella Peck | |
| 3. | Loverboy (2006) | |
| 4. | The Woodsman (2004) as Vickie | |
| 5. | Something the Lord Made (2004) as Mary Blalock | |
| 6. | Cavedweller (2004) as Delia Byrd | |
| 7. | Batman: Mystery of the Batwoman (2003) | |
| 8. | Secondhand Lions (2003) as Mae | |
| 9. | Door to Door (2002) as Shelley Brady | |
| 10. | Just a Kiss (2002) as Halley | |
| 11. | Behind the Red Door (2002) as Natalie | |
| 12. | Personal Velocity (2002) as Delia | |
| 13. | What's Cooking? (2000) as Rachel Seelig | |
| 14. | Montana (1998) as Claire Kelsky | |
| 15. | Kansas (1998) as Prostitute Drifter | |
| 16. | Critical Care (1997) as Felicia Potter | |
| 17. | Losing Chase (1996) as Elizabeth Cole | |
| 18. | Phenomenon (1996) as Lace Pennamin | |
| 19. | Something to Talk About (1995) as Emma Rae | |
| 20. | Murder in the First (1995) as Blanche | |
| 21. | Heart and Souls (1993) as Julia | |
| 22. | Singles (1992) | |
| 23. | Mr. & Mrs. Bridge (1990) as Ruth Bridge | |
| 24. | Born on the Fourth of July (1989) | |
| 25. | Tai-Pan (1986) as Tess Brock | |
| 26. | The Wide Net () | |
| 27. | Pyrates () as Sam |
Producer
| 1. | Loverboy (2006) Producer | |
| 2. | Cavedweller (2004) Executive Producer | |
| 3. | Losing Chase (1996) Executive Producer |
Miscellaneous Crew
| 1. | Montana (1998) Associate Producer |
Most Popular Films with Kyra Sedgwick
| 1. | Gamer | 2009 |
|
| 2. | Singles | 1992 |
|
| 3. | Murder in the First | 1995 |
|
| 4. | Mr. & Mrs. Bridge | 1990 |
|
| 5. | Secondhand Lions | 2003 |
|
| 6. | Heart and Souls | 1993 |
|
| 7. | Losing Chase | 1996 |
|
| 8. | Something the Lord Made | 2004 |
|
| 9. | Batman: Mystery of the Batwoman | 2003 |
|
| 10. | Born on the Fourth of July | 1989 |
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