- Lloyd and his band The Butties released their debut album 12 Greatest Carols in 2005.
- When Sam was younger he grew some chops at the Weston Playhouse and used his father’s Super 8 camera to make home movies.
- Sam's original love of theatre was spawned by his parents who worked at a nearby theatre in his hometown.
- Sam Lloyd attended Syracuse University.
- Lloyd and his band released Riding the Wave, their debut album in 2004.
- Lloyd had a part as a coach in the 1997 hit Flubber.
- Lloyd was a regular in Spin City, another Bill Lawrence-directed show.
- Sam and his cousin Christopher Lloyd both guest starred on an episode of Malcolm in the Middle.
- In 1998, Sam had a starring role in the TV show My Generation. His character name was Verder, Milo.
- Sam Lloyd's career begun when he starred in the series Night Court. In 1988 his character was a waiter in the episode "Harry and the Tramp" and in 1989 his character was a balloon salesman in the episode "Yet Another Day in the Life".
- Sam also plays the bass guitar in a band called The Butties, which is a tribute to the Beatles.
- He is a member of an a capella group The Blanks, sometimes featured on the comedy series Scrubs using the names The Worthless Peon's and Ted's Band.
- He is the nephew of Christopher Lloyd (Back to the Future).
- Son of Sam Lloyd Sr.
- Sam: Who ever knew that losing my hair would create the perfect character for Bill's new show?
- Sam: I remember meeting Neil Flynn for the first time and realizing just how short I really was.
- Sam: Bill Lawrence will always treat you with respect, that's why I never have any problems lining up behind him.
- Sam: My mom gets a little antsy whenever I mention her on the show.
- (in reference to his part in "My Road to Nowhere")
Sam: I hope my mom doesn't see this episode.