Actor
| 1. | The Lady in Question is Charles Busch (2006) as Herself | |
| 2. | Jetsons (2006) as Rosie the Robot (voice) | |
| 3. | Hedwig and the Angry Inch (2001) | |
| 4. | Conan O'Brien's Wild Desk Ride (2001) as Herself/Panelist | |
| 5. | Tarzan (1999) as Terk | |
| 6. | Get Bruce (1999) | |
| 7. | Jackie's Back! (1999) as Herself | |
| 8. | Wide Awake (1998) as Sister Terry | |
| 9. | Elmopalooza (1998) as Herself | |
| 10. | A Very Brady Sequel (1996) | |
| 11. | Beautiful Girls (1996) as Gina Barrisano | |
| 12. | Harriet the Spy (1996) as Ole Golly | |
| 13. | Now and Then (1995) as Dr. Roberta Martin | |
| 14. | I'll Do Anything (1994) | |
| 15. | Car 54, Where Are You? (1994) as Lucille Toody | |
| 16. | The Flintstones (1994) as Betty Rubble | |
| 17. | Exit to Eden (1994) as Sheila Kingston | |
| 18. | Fatal Instinct (1993) as Woman in Bird Store | |
| 19. | Another Stakeout (1993) as Assistant D.A. Gina Garrett | |
| 20. | Sleepless in Seattle (1993) as Becky | |
| 21. | A League of Their Own (1992) as Doris Murphy - 3B |
Most Popular Films with Rosie O'Donnell
| 1. | Fatal Instinct | 1993 |
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| 2. | The Flintstones | 1994 |
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| 3. | A Very Brady Sequel | 1996 |
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| 4. | Elmopalooza | 1998 |
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| 5. | Exit to Eden | 1994 |
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| 6. | Tarzan | 1999 |
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| 7. | Harriet the Spy | 1996 |
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| 8. | Now and Then | 1995 |
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| 9. | A League of Their Own | 1992 |
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| 10. | Sleepless in Seattle | 1993 |
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