Professor Utonium has stocked up on sugar, spice and everything nice in hopes of creating the perfect little girls. While concocting the special brew, an accident leads to the adding of the...

Professor Utonium has stocked up on sugar, spice and everything nice in hopes of creating the perfect little girls. While concocting the special brew, an accident leads to the adding of the mysterious Chemical X to the pot. What results is three superpowered little girls, making the professor an instant parent to three lovely but difficult charges. The first day of school at Pokey Oaks kindergarten reveals they are more than the sweet new students Ms. Keane and the other children see at first glance. A playground game of tag leads to the destruction of Townsville when the girls kick their powers into high gear. The entire town blames them for the fallout, the professor is arrested, and the girls have their first run-in with Jojo on their long walk home. He convinces them that if they just help him bring his great plan to fruition, the town will be a better place and everyone will love them for it. When Blossom, Bubbles and Buttercup see the plan's results, however, they recognize they have been duped. After an extraterrestrial bout of self-pity and fighting, the three return to Townsville to save its residents from Mojo Jojo's horde of large-brained monkeys and apes and their efforts to gain supreme control. But they don't discover the true value of powers until they realize the futility of trying to save every man, woman, child and dog from simian wrath and decide to take on the bad guys directly. Once the butt-kicking is over, the town welcomes the girls' powers and the mayor invites them to save the day on a regular basis. And so, for the first time, the city of Townsville is saved, thanks to the Powerpuff Girls.